About Atopic Dermatitis
Atopic dermatitis is an acute, subacute, or chronic relapsing skin disorder that usually begins in infancy and is characterized principally by dry skin and pruritis ( itching); consequent rubbing and scratching lead to lichenification (thickening) and hence to further itching and scratching (itch-scratch-cycle). The diagnosis is based on clinical findings. Atopic dermatitis is often associated with a personal or family history of atopic dermatitis, allergic rhinitis, and asthma. 35% of infants with atopic dermatitis develop asthma later in life. There is a strong genetic etiology underlying the predisposition to develop atopic dermatitis. In addition to the genetic predisposition, other eliciting factors include allergens (topical, inhalant, oral), microbial agents, disruptions in the skin barrier, infections, seasonal exacerbations, clothing, and stress.